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A year in review Economic / Governance Environment Social Appendix Innovation capabilities & management We use, for instance, blue, green and white biotechnology Animal-free testing techniques where possible. This involves creating ingredients In addition to these pillars, we are also looking to abolish the use PLANETCAPS™ using living organisms or enzymes, allowing us to create of animals in cosmetic testing. Givaudan was the first fragrance Cutting edge fragrance products that are eco-responsible, use less energy and company to invest in exploring animal-testing alternatives, and generate less waste. Givaudan’s expertise in blue we continue to lead in this area, researching and developing technology biotechnologies draws on molecules and active ingredients non-invasive ways to test new molecules and ensure the safety found in the ocean, highly sustainable resources offering of our products, all while speeding up the testing process. Givaudan scientists have been striving for powerful beauty properties. White biotechnology allows the last six years to ensure fragrances scientists to create active cosmetic ingredients through the The programme includes our OECD validated KeratinoSens®, a capsules both deliver outstanding scent use of microorganisms or enzymes, which are natural leading non-animal test for skin sensitisation, and PebitoSens™, release and are kind to nature. processes that result in the use of eco-friendly solvents. Green a combination of in vitro methods for bioaccumulation and PlanetCaps™, a result of their work, are biotechnology and advanced extraction techniques allow us acute fish toxicity which involves testing fish cells and enzymes based on an industry-leading to reduce waste by using all parts of the plant. A recent rather than living fish. encapsulation innovation that enables partnership with Bio FD&C, a leader in plant cell culture, long-lasting fragrance in a biodegradable allowed us to explore ways of leveraging the untapped This year, the world’s first toxicology testing strategy without and bio-sourced delivery system for fabric properties of plants through stem cell cultures and animal testing, developed and validated in a joint effort by softeners. A combination of high phytopeptides. This has already allowed us to introduce Givaudan and BASF, was approved by the OECD (Organisation biodegradability and renewable carbon unique new active ingredients for hair and skincare such as for Economic Co-operation and Development). The strategy source material, PlanetCaps™ deliver K-Phyto™ Camelia and K-Phyto™ GHK. consists of three alternative methods that can be used to long-lasting fragrance experience that is predict whether a substance causes allergic reactions in the appreciated by both customers and We also look to optimise the use of the renewable biomass skin. We also developed the Kinetic DPRA, another alternative consumers. Their introduction allows available locally, for example at our unique biorefinery method that allows researchers to predict how intense an Givaudan’s customers to achieve the platform in Pomacle, France. This biocatalysis plant helps us allergic reaction in the skin might be without animal testing. complex balance between greenness and prevent waste, be more economical, use less hazardous, safer Validated in partnership with the chemical company BASF and performance in fabric softeners, one of chemicals and solvents, rely on renewable feedstocks, and be other institutions, the test received OECD approval this year. the consumer goods’ applications that more biodegradable in the environment. As an example, the This battery of tests complements the now approved testing relies most on capsules. The introduction enzymes that lie at the core of biocatalysis can transform strategy and allows us to create new molecules that are safe of PlanetCaps™ makes Givaudan the first leftover residues and are a prime source of renewable raw for customers without animal testing. fragrance house to offer a fully scaled materials. The result is a suite of authentically ‘green’ active solution ahead of the European Chemicals cosmetic ingredients that can be used by customers Givaudan also took its commitment to animal-free testing to Agency’s proposed restriction on committed to sustainably developing their products. the next level by joining the Animal-Free Safety Assessment microplastics, due for ratification in 2022. Collaboration. The AFSA brings together corporations with non- The cutting-edge fragrance technology profit organisations such as Humane Society International (HSI), will be expanded to other categories, who share the vision of a non-animal approach to product helping us boost sustainability. safety assessment to better protect people and our planet. 45 Givaudan — 2021 GRI Sustainability Report

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